Drug Profile


Alternative Names: AD 32; N-Trifluoroacetyladriamycin-14-valerate; NSC 246131; Valstar; Valtaxin

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Anthra Pharmaceuticals
  • Developer Endo Pharmaceuticals Solutions
  • Class Anthracyclines; Antineoplastics; Cytostatics; Small molecules
  • Mechanism of Action DNA repair enzyme inhibitors; Reactive oxygen species stimulants; Type II DNA topoisomerase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Marketed Bladder cancer
  • Discontinued Endometrial cancer; Ovarian cancer

Most Recent Events

  • 24 Jul 2012 CTP alert for NCT01606345 - Endo Pharma is only the collaborator - not added
  • 14 Feb 2012 Endo Pharmaceuticals terminates a phase III trial in Bladder cancer in USA (NCT01310803)
  • 18 Jul 2011 Endo Pharmaceuticals initiates enrolment in a phase III trial for Bladder cancer in USA (NCT01310803)
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