Neridronic acid

Drug Profile

Neridronic acid

Alternative Names: AHDP; AHHexBP; Aminohexane diphosphonate; Attila; Neridronate; Nerixia

Latest Information Update: 03 Jan 2017

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At a glance

  • Originator Istituto Gentili
  • Developer Abiogen Pharma; Austin Pain Associates; Grunenthal; Lees Pharmaceutical Holdings; Shire Pharmaceuticals Group
  • Class Bisphosphonates; Calcium regulators; Small molecules
  • Mechanism of Action Bone resorption factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Reflex sympathetic dystrophy
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Osteitis deformans; Osteogenesis imperfecta
  • Registered Complex regional pain syndromes
  • Discontinued Malignant hypercalcaemia; Postmenopausal osteoporosis

Most Recent Events

  • 16 Dec 2016 Neridronic acid receives Breakthrough Therapy status for Complex regional pain syndrome in USA
  • 01 Dec 2016 Phase-III clinical trials in Complex regional pain syndrome in USA (IV) (NCT02972359)
  • 21 Nov 2016 Grunenthal plans a phase III trial for Complex regional pain syndrome in USA (NCT02972359)
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