Motexafin lutetium

Drug Profile

Motexafin lutetium

Alternative Names: Antrin®; FP FP1; Lu-Tex; Lu-Tex/OPTRIN; Lutetium texaphyrin; Lutrin®; Optrin™; PCI 0123

Latest Information Update: 09 Jul 2007

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At a glance

  • Originator Pharmacyclics
  • Class Antineoplastics; Oxidants; Texaphyrins
  • Mechanism of Action Photosensitisers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Age-related macular degeneration; Atherosclerosis; Breast cancer; Cervical intraepithelial neoplasia; Coronary artery restenosis; Peripheral arterial disorders; Prostate cancer; Vascular restenosis

Most Recent Events

  • 28 Mar 2006 Motexafin lutetium is available for licensing worldwide (
  • 15 Nov 2004 Data presented at the American Heart Association Scientific Sessions (AHA-2004) have been added to the Ischaemic Heart Disease pharmacodynamics section
  • 12 Oct 2004 Data presented at the 16th Annual Transcatheter Cardiovascular Therapeutics conference (TCT-2004) have been added to the Ischaemic Heart Disease therapeutic trials section
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