Natalizumab - Biogen/Perrigo

Drug Profile

Natalizumab - Biogen/Perrigo

Alternative Names: AN 10022; AN 100226; Antegren; Anti-alpha4 integrin monoclonal antibody; BG-00002; BG-0002; BG-0002-E; Tysabri

Latest Information Update: 04 Nov 2017

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At a glance

  • Originator Elan Corporation
  • Developer Biogen; Biogen Idec; Elan Corporation; Perrigo
  • Class Antineoplastics; Monoclonal antibodies; Vascular disorder therapies
  • Mechanism of Action Integrin alpha4beta1 antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Crohn's disease; Multiple sclerosis
  • Phase II Epilepsy; Graft-versus-host disease; Stroke
  • Discontinued Multiple myeloma; Rheumatoid arthritis

Most Recent Events

  • 04 Nov 2017 No recent reports of development identified for phase-I development in Multiple-sclerosis in USA (IM)
  • 04 Nov 2017 No recent reports of development identified for phase-I development in Multiple-sclerosis in USA (SC)
  • 04 Nov 2017 No recent reports of development identified for phase-I development in Multiple-sclerosis(In adolescents, In children) in Italy (IV, Infusion)
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