Research programme: single-stranded oligonucleotide based therapeutics - Gentium

Drug Profile

Research programme: single-stranded oligonucleotide based therapeutics - Gentium

Alternative Names: Nmers; Oligotide

Latest Information Update: 28 Feb 2014

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At a glance

  • Originator Crinos Biological Research Laboratories
  • Developer Gentium
  • Class Oligonucleotides
  • Mechanism of Action Cell membrane modulators; Heparanase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Diabetic nephropathies
  • Discontinued Chemotherapy-induced damage; Myocardial ischaemia

Most Recent Events

  • 21 Feb 2014 Gentium has been acquired by Jazz Pharmaceuticals plc
  • 28 Oct 2010 Preclinical development is ongoing Italy
  • 31 Jan 2008 Preclinical trials in Kidney disorders in Italy (unspecified route)
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