Drug Profile


Alternative Names: Anti-EGFR monoclonal antibody; EMD 72000

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator ImClone Systems
  • Developer Merck KGaA; Takeda
  • Class Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Epidermal growth factor inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Cervical cancer; Colorectal cancer; Gastric cancer; Head and neck cancer; Non-small cell lung cancer; Ovarian cancer

Most Recent Events

  • 20 Feb 2008 Takeda together with Merck have decided to jointly discontinue development of matuzumab for all indications
  • 20 Feb 2008 Discontinued - Phase-II for Cervical cancer in Europe (IV)
  • 20 Feb 2008 Discontinued - Phase-II for Colorectal cancer in European Union (IV)
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