Drug Profile


Alternative Names: Gelsolin recombinant; hu r-P gelsolin; pGSN; Recombinant human plasma gelsolin; rh gelsolin; Solinex

Latest Information Update: 28 Oct 2017

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At a glance

  • Originator Brigham and Womens Hospital
  • Developer BioAegis Therapeutics; Critical Biologics Corporation
  • Class Antineoplastics; Expectorants; Proteins
  • Mechanism of Action Undefined mechanism
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Community-acquired pneumonia
  • Discontinued Bronchitis; Cystic fibrosis; Systemic inflammatory response syndrome

Most Recent Events

  • 04 Oct 2017 Preclinical pharmacodynamics data in Pneumonia presented at the IDWeek 2017 (IDW-2017)
  • 09 Jun 2016 Phase-I/II clinical trials in Community-acquired pneumonia in USA (Parenteral)
  • 20 May 2015 BioAegis plans a phase II trial in Pneumonia in Europe
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