Drug Profile


Alternative Names: Axokine; Ciliary neurotrophic factor - Regeneron; pegAxokine; RG228

Latest Information Update: 03 Aug 2007

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At a glance

  • Originator Regeneron Pharmaceuticals
  • Developer Emisphere Technologies; Regeneron Pharmaceuticals
  • Class Eye disorder therapies; Obesity therapies
  • Mechanism of Action Ciliary neurotrophic factor replacements
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Discontinued Amyotrophic lateral sclerosis; Huntington's disease; Obesity; Retinal disorders

Most Recent Events

  • 31 Dec 2006 Discontinued - Phase-III for Obesity in USA (SC)
  • 31 Dec 2006 Discontinued - Preclinical for Retinal disorders in USA (unspecified route)
  • 16 May 2006 No development reported - Phase-III for Obesity in USA (SC)
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