Drug Profile


Alternative Names: Anti-CD11a monoclonal antibody - Genentech/Xoma; HU 1124; Hu1124; Raptiva; Xanelim™

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Genentech
  • Developer Genentech; Merck Serono; XOMA
  • Class Monoclonal antibodies
  • Mechanism of Action CD11a antigen antagonists; Immunosuppressants; T cell activation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Marketed Psoriasis
  • Discontinued Psoriatic arthritis; Type 1 diabetes mellitus

Most Recent Events

  • 17 Apr 2016 Biomarkers information updated
  • 11 Jun 2009 Withdrawn for Psoriasis in Canada (SC)
  • 08 Jun 2009 Withdrawn for Psoriasis in European Union (SC)
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