Drug Profile


Alternative Names: Aquilda; SR 121463B; SR-121463

Latest Information Update: 02 Jun 2010

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At a glance

  • Originator sanofi-aventis
  • Class Antihypertensives; Heart failure therapies; Morpholines; Small molecules; Spiro compounds
  • Mechanism of Action Vasopressin V2 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Glaucoma; Heart failure; Hypertension; Hyponatraemia; Liver cirrhosis; Nephrotic syndrome

Most Recent Events

  • 26 Apr 2009 Adverse events data from a trial in liver cirrhosis presented at the 44th Annual Meeting of the European Association for the Study of the Liver (EASL-2009)
  • 31 Dec 2008 Discontinued - Phase-III for Cirrhosis in Argentina (PO)
  • 31 Dec 2008 Discontinued - Phase-III for Cirrhosis in Australia (PO)
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