Exenatide - AstraZeneca

Drug Profile

Exenatide - AstraZeneca

Alternative Names: AC 2993; AC002993; AC2993A; Byetta; Exendin 4; LY2148568

Latest Information Update: 25 Oct 2017

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At a glance

  • Originator Amylin Pharmaceuticals
  • Developer AstraZeneca; Radboud University; Regional and University Hospital of Besancon
  • Class Antihyperglycaemics; Obesity therapies; Peptides; Venoms
  • Mechanism of Action Glucagon like peptide 1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Type 2 diabetes mellitus
  • Phase II/III Metabolic disorders; Type 1 diabetes mellitus
  • Phase II Obesity

Most Recent Events

  • 12 Oct 2017 The Committee for Medicinal Products for Human Use recommends approval to extend the use of exenatide in combination with basal insulin for Type-2 diabetes mellitus in European Union
  • 24 Jul 2017 Exenatide is still in phase III trials for Type-2 diabetes mellitus (In adolescents) in USA, India, Mexico and South Korea (SC) (NCT00658021)
  • 24 Jul 2017 Phase-II/III development for Perioperative stress hyperglycaemia is ongoing in France (IV)(NCT01969149)
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