Pirfenidone

Drug Profile

Pirfenidone

Alternative Names: AMR 69; Deskar; Esbriet; Etuary; F 647; Pirespa; RO 0220912; S 7701

Latest Information Update: 20 May 2017

Price : $50

At a glance

  • Originator KDL Gmbh; Marnac
  • Developer AFT Pharmaceuticals; Beijing Continent Pharmaceutical; Il Dong; Roche; Shanghai Genomics; Shionogi
  • Class Anti-inflammatories; Antifibrotics; Pyridones; Small molecules
  • Mechanism of Action Collagen inhibitors; Cytokine inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Idiopathic pulmonary fibrosis; Interstitial lung diseases
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Idiopathic pulmonary fibrosis
  • Phase II Acute lung injury; Heart failure; Interstitial lung diseases
  • Preclinical Diabetic nephropathies
  • Discontinued Glomerulonephritis; Multiple sclerosis; Peritoneal fibrosis; Renal fibrosis; Retinal disorders; Scleroderma

Most Recent Events

  • 18 Apr 2017 Phase-II clinical trials in Interstitial lung diseases in Spain (PO) (EudraCT2016-002744-17) (NCT03099187)
  • 04 Mar 2017 Pirfenidone is still in phase II development for Interstitial lung disease in USA (NCT02958917)
  • 04 Mar 2017 National Jewish Health and Genentech initiates a phase II trial in Interstitial lung disease in USA (NCT02958917)
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