Vitamin D binding protein macrophage-activating factor

Drug Profile

Vitamin D binding protein macrophage-activating factor

Alternative Names: EF-022; GcMAF; Globulin component macrophage activating factor

Latest Information Update: 27 Jun 2017

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At a glance

  • Originator Einstein Medical Center
  • Developer Efranat; Socrates Institute for Therapeutic Immunology
  • Class Antineoplastics; Carrier proteins; Lymphokines
  • Mechanism of Action Macrophage activating factor replacements; Macrophage stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I Solid tumours
  • Preclinical Recurrent respiratory papillomatosis
  • Discontinued Breast cancer; Colorectal cancer; Prostate cancer

Most Recent Events

  • 27 Jun 2017 Discontinued - Phase-I for Breast cancer (Metastatic disease) in USA (IM)
  • 27 Jun 2017 Discontinued - Phase-I for Colorectal cancer (Metastatic disease) in USA (IM)
  • 27 Jun 2017 Discontinued - Phase-I for Prostate cancer in USA (IM)
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