Peginterferon alfa-2a

Drug Profile

Peginterferon alfa-2a

Alternative Names: PEG IFN-α-2a; PEG interferon-α-2a; Pegasys; Pegferon; Pegylated interferon-alpha-2a; R 442; RG 442; RG 964; RO 25-8310; RO 253036

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Roche
  • Developer Chugai Pharmaceutical; Roche; University of Pennsylvania
  • Class Antivirals; Interferons; Polyethylene glycols
  • Mechanism of Action Immunostimulants; Interferon alpha stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Hepatitis B; Hepatitis C
  • Phase III Chronic myeloid leukaemia; Hepatitis D
  • Phase II HIV-1 infections
  • Discontinued Malignant melanoma; Renal cell carcinoma

Most Recent Events

  • 11 Nov 2016 Adverse events and efficacy data from a phase III trial in Hepatitis B (In adolescents, In children) presented at The Liver Meeting 2016: 67th Annual Meeting of the American Association for the Study of Liver Diseases (AASLD-2016)
  • 29 Jul 2016 Discontinued - Phase-II/III for Chronic myeloid leukaemia in Spain, Slovakia, South Africa, India, Canada, Bulgaria (SC) (Roche pipeline; July 2016)
  • 29 Jul 2016 Discontinued - Phase-II/III for Malignant melanoma in Spain, South Africa, India, Slovakia, Canada, Bulgaria (SC) (Roche pipeline; July 2016)
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