Drug Profile


Alternative Names: ED 749; J-107088; PF-804950; PHA-782615

Latest Information Update: 21 Aug 2009

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At a glance

  • Originator Banyu; Merck & Co
  • Class Antineoplastics; Carbazoles; Indoles
  • Mechanism of Action DNA topoisomerase I inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Cancer; Colorectal cancer; Glioblastoma

Most Recent Events

  • 17 Jan 2006 Discontinued - Phase-III for Glioblastoma in USA (IV-injection)
  • 17 Jan 2006 Data presented at the 13th European Cancer Conference (ECCO-2005) have been added to the Cancer therapeutic trials section
  • 05 Apr 2005 Pfizer has terminated its license for edotecarin worldwide
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