Drug Profile


Alternative Names: Adexor; Flavedon; Idaptan; Preductal; S 5016; Trimetazine; Vastarel; Vastarel F; Vastinan

Latest Information Update: 18 Jul 2014

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At a glance

  • Originator Servier
  • Class Anti-ischaemics; Ischaemic heart disorder therapies; Piperazines; Small molecules; Vasodilators
  • Mechanism of Action Adenosine triphosphatase inhibitors; Antioxidants; Calcium channel antagonists; Free radical scavengers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Marketed Angina pectoris; Eye disorders; Ischaemic heart disorders; Tinnitus; Vertigo

Most Recent Events

  • 15 Dec 2016 Biomarkers information updated
  • 19 Jun 2014 Dainippon Sumitomo Pharma is now called Sumitomo Dainippon Pharma
  • 22 Jun 2012 The European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) recommended that trimetazidine is not used for treatment of vertigo, tinnitus or vision disturbance, and the deletion of these indications from the marketing authorisation .
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