Botulinum toxin A injectable - Allergan

Drug Profile

Botulinum toxin A injectable - Allergan

Alternative Names: Botox; GSK 1358820; Onabotulinum toxin A; Vistabel; Vistabex

Latest Information Update: 24 Jul 2017

Price : $50

At a glance

  • Originator Allergan
  • Developer Allergan; GlaxoSmithKline; Johns Hopkins University; Temple University; Wake Forest University School of Medicine
  • Class Antispasmodics; Bacterial proteins; Bacterial toxins; Botulinum toxins; Muscle relaxants
  • Mechanism of Action Acetylcholine inhibitors; Glutamate receptor antagonists; Glutamate-antagonists; Neuromuscular blocking agents; Substance P release inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Muscle spasticity; Torticollis
  • New Molecular Entity No

Highest Development Phases

  • Marketed Blepharospasm; Facial-wrinkles; Glabellar lines; Hyperhidrosis; Migraine; Muscle spasticity; Neurogenic bladder; Overactive bladder; Strabismus; Torticollis
  • Registered Equinus foot deformity
  • Phase III Raynaud's disease
  • Phase II Herpes labialis; Hypertrophy; Major depressive disorder; Musculoskeletal pain; Pain; Premature ejaculation
  • Phase I/II Pruritus
  • No development reported Benign prostatic hyperplasia
  • Discontinued Diabetic gastroparesis; Gilles de la Tourette's syndrome

Most Recent Events

  • 19 Jul 2017 Allergan files an IND application with the US FDA for Overactive bladder
  • 12 Jul 2017 Allergan withdrawn a phase III trial in Migraine (Prevention) prior to enrolment due to corporate decision (NCT03193359)
  • 12 Jul 2017 Allergan withdrawn a phase III trial in Migraine prior to enrolment due to corporate decision (NCT03193346)
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at AsktheExpert.AdisInsight@springer.com so we can help.

Back to top