Botulinum toxin A - Allergan

Drug Profile

Botulinum toxin A - Allergan

Alternative Names: AGN 191622; Botox; GSK 1358820; Oculinum; Onabotulinum toxin A; Vistabel; Vistabex

Latest Information Update: 11 Apr 2017

Price : $50

At a glance

  • Originator Allergan
  • Developer Allergan; GlaxoSmithKline; Johns Hopkins University; Wake Forest University School of Medicine
  • Class Antispasmodics; Bacterial proteins; Bacterial toxins; Botulinum toxins; Muscle relaxants
  • Mechanism of Action Acetylcholine inhibitors; Glutamate receptor antagonists; Glutamate-antagonists; Neuromuscular blocking agents; Substance P release inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Muscle spasticity; Torticollis
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Blepharospasm; Facial-wrinkles; Glabellar lines; Hyperhidrosis; Migraine; Muscle spasticity; Neurogenic bladder; Overactive bladder; Strabismus; Torticollis
  • Registered Equinus foot deformity
  • Phase III Raynaud's disease
  • Phase II Herpes labialis; Hypertrophy; Major depressive disorder; Musculoskeletal pain; Pain; Premature ejaculation
  • No development reported Benign prostatic hyperplasia
  • Discontinued Diabetic gastroparesis; Gilles de la Tourette's syndrome

Most Recent Events

  • 05 Apr 2017 Allergan plans a phase III trial for Major depressive disorders
  • 05 Apr 2017 Final efficacy and adverse events data from a phase II trial in Major depressive disorders released by Allergan
  • 13 Feb 2017 The Scottish Medicines Consortium advices restricted use of botulinum toxin A within NHS Scotland
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