Drug Profile


Alternative Names: AC-820; MT-9938; Nalfurafine hydrochloride; Nopicor; REMITCH; TRK-820; Winfuran

Latest Information Update: 03 Aug 2017

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At a glance

  • Originator Toray
  • Developer Fresenius Medical Care; Japan Tobacco; Maruho; Mitsubishi Tanabe Pharma Corporation; SK Chemicals; Toray; Torii Pharmaceutical
  • Class Antipruritics; Morphinans; Opioid analgesics; Small molecules; Spiro compounds
  • Mechanism of Action Opioid kappa receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Pruritus
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Pruritus
  • Discontinued Atopic dermatitis; Cancer pain; Neuropathic pain

Most Recent Events

  • 01 Jul 2017 Toray Industries completes a phase I trial in Pruritus in Bulgaria and Germany (PO) (NCT03002233)
  • 30 Mar 2017 Registered for Pruritus (Treatment-experienced) in Japan (PO, Tablet)
  • 01 Nov 2016 Phase-I clinical trials in Pruritus in Bulgaria, Germany (PO) (NCT03002233)
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