Drug Profile


Alternative Names: R 093877; R 108512; R 93877; Resolor; Resotran; Resotrans; Rezolor; SHP555; SPD-555

Latest Information Update: 25 Mar 2017

Price : $50

At a glance

  • Originator Janssen
  • Developer Janssen; Shire-Movetis NV; University of Calgary
  • Class Amides; Benzofurans; Gastrokinetics; Irritable bowel syndrome therapies; Piperidines; Small molecules
  • Mechanism of Action Serotonin 4 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Constipation
  • Phase II/III Diabetic gastroparesis
  • No development reported Postoperative ileus

Most Recent Events

  • 15 Dec 2015 Shire plans a phase III trial for Constipation in USA
  • 19 Mar 2015 Prucalopride is still in phase III trials for Constipation in USA
  • 19 Mar 2015 No recent reports on development identified - Phase-III for Constipation (In adolescents, In children, In infants) in European Union (PO)
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