Esomeprazole

Drug Profile

Esomeprazole

Alternative Names: D961H; Esomeprazole delayed-release capsules; Esomeprazole magnesium; Esoz; H-19918; H-19918 magnesium trihydrate; H199/18 magnesium trihydrate; Nexium; Nexium 24HR; Nexium Control; Nexium I.V.; Perprazole; S-omeprazole magnesium

Latest Information Update: 03 Feb 2017

Price : $50

At a glance

  • Originator AstraZeneca
  • Developer AstraZeneca; Pfizer
  • Class 2 pyridinylmethylsulfinylbenzimidazoles; Antiulcers; Gastric antisecretories; Small molecules
  • Mechanism of Action Proton pump inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Bleeding ulcer; Gastro-oesophageal reflux; Heartburn; Helicobacter infections; NSAID-induced ulcer; Peptic ulcer; Reflux oesophagitis; Zollinger-Ellison syndrome
  • Preregistration Stress ulcer
  • Phase III Duodenal ulcer; Gastric ulcer; Jejunal ulcer

Most Recent Events

  • 03 Feb 2017 Preregistration for Stress ulcer (Prevention) in China (IV) before February 2017 (AstraZeneca pipeline, February 2017)
  • 03 May 2016 Launched for Heartburn in USA before May 2016 (PO, Tablet)
  • 01 Apr 2016 AstraZeneca completes a phase III trial for Duodenal ulcer, Gastric ulcer, Jejunal ulcer (anastomotic ulcer), Reflux oesophagitis and Zollinger-Ellison syndrome (in children aged 1 to 14 years) in Japan (NCT02153398)
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at AsktheExpert.AdisInsight@springer.com so we can help.

Back to top