Research programme: recombinant human alpha-1 antitrypsin - rEVO Biologics

Drug Profile

Research programme: recombinant human alpha-1 antitrypsin - rEVO Biologics

Alternative Names: AAT - GTC; Alpha-1 proteinase inhibitor - GTC; Alpha-1-antitrypsin - GTC; rhAAT - GTC; TgAAT - GTC

Latest Information Update: 21 Feb 2013

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At a glance

  • Originator GTC Biotherapeutics; LFB Biotechnologies
  • Developer rEVO Biologics
  • Class Acute-phase proteins; Alpha globulins; Blood proteins; Secretory proteinase inhibitory proteins; Serpins
  • Mechanism of Action Pancreatic elastase inhibitors; Serine endopeptidase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • Available For Licensing Yes - Alpha 1-antitrypsin deficiency

Highest Development Phases

  • Preclinical Alpha 1-antitrypsin deficiency

Most Recent Events

  • 04 Jan 2013 GTC Biotherapeutics is now called rEVO Biologics
  • 07 Dec 2010 GTC Biotherapeutics has been acquired by LFB Biotechnologies
  • 31 Dec 2009 Alpha-1 antitrypsin is available for licensing (
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