Cinacalcet

Drug Profile

Cinacalcet

Alternative Names: 226256-56-0; AMG-073; Cinacalcet HCL; Cinacalcet hydrochloride; KRN-1493; Mimpara; NPS-1493; Regpara; Sensipar

Latest Information Update: 10 Jul 2017

Price : $50

At a glance

  • Originator NPS Pharmaceuticals
  • Developer Amgen; Kirin Holdings Company
  • Class Naphthalenes
  • Mechanism of Action Calcium channel agonists; Parathyroid hormone receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Hypercalcaemia
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Hypercalcaemia; Primary hyperparathyroidism; Secondary hyperparathyroidism
  • No development reported Cardiovascular disorders

Most Recent Events

  • 23 Jun 2017 Preregistration for Secondary hyperparathyroidism (In adolescents, In children) in European Union (PO) before June 2017
  • 23 Jun 2017 The EMA's CHMP adopts a positive opinion for cinacalcet in Secondary hyperparathyroidism (In children, Treatment-experienced)
  • 15 Mar 2017 Amgen completes a phase III extension trial in Secondary hyperparathyroidism (In adolescents, In children) in USA, Belgium, Czech Republic, France, Germany, Greece, Hungary, Italy, Poland, Russia and Ukraine (NCT02341417)
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