Cinacalcet

Drug Profile

Cinacalcet

Alternative Names: 226256-56-0; AMG-073; Cinacalcet hydrochloride; KRN-1493; Mimpara; NPS-1493; Regpara; Sensipar

Latest Information Update: 25 Mar 2017

Price : $50

At a glance

  • Originator NPS Pharmaceuticals
  • Developer Amgen; Kirin Holdings Company
  • Class Naphthalenes
  • Mechanism of Action Calcium channel agonists; Parathyroid hormone receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Hypercalcaemia
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Hypercalcaemia; Primary hyperparathyroidism; Secondary hyperparathyroidism
  • No development reported Cardiovascular disorders

Most Recent Events

  • 14 Feb 2017 Amgen has patent protection for cinacalcet in USA and European Union (Amgen 10-K, February 2017)
  • 21 Oct 2016 Preregistration for Secondary hyperparathyroidism in Brunei (PO) (Kyowa Hakko Kirin pipeline, October 2016)
  • 22 Jun 2016 Amgen terminates a phase II trial in Secondary hyperparathyroidism (In children, In adolescents) in USA, Belgium, Czech Republic, France, Germany, Hungary, Italy, Mexico, the Netherlands, New Zealand, Poland, Russia and Slovakia (NCT01439867)
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