Drug Profile


Alternative Names: AM 424; Leukaemia inhibitory factor; Leukemia inhibitory factor; LIF; recombinant leukaemia inhibitory factor; Recombinant leukaemia inhibitory factor protein - Ares-Serono; Recombinant LIF protein - Ares-Serono; rhLIF

Latest Information Update: 02 May 2005

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At a glance

  • Originator Walter and Eliza Hall Institute of Medical Research
  • Class Cytokines; Neuroprotectants
  • Mechanism of Action Leukaemia inhibitory factor stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Female infertility; Neuromuscular disorders

Most Recent Events

  • 23 Jun 2004 Data from a media release have been added to the Women's Health therapeutic trials section
  • 04 Jun 2004 Serono has completed the international proof-of-concept phase II trial with emfilermin for female infertility
  • 07 Jul 2003 Data from a media release have been added to the adverse events and Women's health therapeutic trials sections
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