Drug Profile


Alternative Names: BMS 186716; BMS 186716-01; Vanlev

Latest Information Update: 10 Jan 2007

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At a glance

  • Originator Bristol-Myers Squibb
  • Class Antihypertensives; Pyridines; Small molecules; Thiazepines
  • Mechanism of Action ACE inhibitors; Endopeptidase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Angina pectoris; Heart failure; Hypertension; Myocardial infarction

Most Recent Events

  • 26 May 2003 Data presented at the 18th Annual meeting of the American Society of Hypertention (ASH-2003) have been added to the Hypertension pharmacodynamics section
  • 15 Oct 2002 The FDA have issued Bristol-Myers Squibb with an action letter regarding approval of Vanlev®
  • 24 Sep 2002 A study has been added to the adverse events and Heart Failure therapeutic trials sections
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