Drug Profile


Alternative Names: MCP-101; RTX

Latest Information Update: 12 Dec 2017

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At a glance

  • Originator National Institutes of Health (USA)
  • Developer ICOS Corporation; Mt Cook Pharma; National Institutes of Health (USA); Sorrento Therapeutics
  • Class Analgesics
  • Mechanism of Action TRPV cation channel agonists; TRPV1 receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cancer pain
  • New Molecular Entity Yes

Highest Development Phases

  • Phase I/II Cancer pain
  • Discontinued Interstitial cystitis; Overactive bladder; Rhinitis

Most Recent Events

  • 29 Nov 2017 Sorrento and National Institutes of Health (USA) re-initiates enrolment in a phase I/II trial for Cancer pain in USA (Intrathecal) (NCT00804154)
  • 01 Aug 2017 Phase-I clinical trials in Cancer pain in USA (Epidural) (NCT03226574)
  • 30 Jun 2017 Sorrento Therapeutics plans a phase II trial for Cancer pain in late 2017
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