Drug Profile


Alternative Names: Entyvio; Kynteles; LDP-02; LPD-02; MLN-0002; MLN-002; MLN-02

Latest Information Update: 19 Jul 2017

Price : $50

At a glance

  • Originator Millennium Pharmaceuticals
  • Developer Medical College of Wisconsin; Millennium; Takeda; Takeda Oncology
  • Class Anti-inflammatories; Antineoplastics; Monoclonal antibodies
  • Mechanism of Action Alpha4-beta7 integrin antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Crohn's disease; Ulcerative colitis
  • Phase II Graft-versus-host disease
  • Phase I Malignant melanoma

Most Recent Events

  • 14 Jul 2017 Takeda plans a phase III trial for Ulcerative colitis (Treatment-experienced, In adults, In the elderly) in China (IV) (NCT03221036)
  • 28 Jun 2017 Phase-II clinical trials in Crohn's disease (In children, In adolescents) in USA (IV) (NCT03138655)
  • 28 Jun 2017 Phase-II clinical trials in Ulcerative colitis (In children, In adolescents) in USA (IV) (NCT03138655)
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