Drug Profile


Alternative Names: A-796874.0; ABT-874; Anti-IL-12/23-antibody-Abbott; BSF 415977; J 695; LU 415977; Ozespa; WAY-165772

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Cambridge Antibody Technology
  • Developer Abbott GmbH & Co. KG
  • Class Monoclonal antibodies
  • Mechanism of Action Interleukin 12 inhibitors; Interleukin 23 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preregistration Submission Withdrawal Plaque psoriasis
  • Discontinued Crohn's disease; Multiple sclerosis; Rheumatoid arthritis

Most Recent Events

  • 02 Jan 2013 Abbott separates its pharmaceuticals business to new company called AbbVie
  • 01 Oct 2011 Abbott Laboratories completes a phase III trial in Plaque psoriasis in Canada, Switzerland, USA and the European Union (NCT00626002)
  • 14 Jan 2011 Regulatory submission withdrawn for Plaque psoriasis in USA (SC)
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