Estradiol topical - Orion

Drug Profile

Estradiol topical - Orion

Alternative Names: Divigel; Estradiol gel - Orion; Estradiol hemihydrate; Gynpolar; Sandrena; Sisare Gel Mono

Latest Information Update: 27 Mar 2014

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At a glance

  • Originator Orion
  • Developer Merck & Co; POLA PHARMA; Vertical Pharmaceuticals
  • Class Antineoplastics; Estradiol congeners; Estrenes; Hormonal replacements; Small molecules
  • Mechanism of Action Estrogen receptor agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Marketed Postmenopausal osteoporosis; Vasomotor symptoms

Most Recent Events

  • 24 Mar 2014 Vertical Pharmaceuticals acquires estradiol topical from Upsher-Smith in USA
  • 20 Aug 2013 Biomarkers information updated
  • 30 Jun 2009 Final efficacy and adverse events data from a phase III trial in Vasomotor symptoms released by Upsher-Smith Laboratories
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