Collagenase injection

Drug Profile

Collagenase injection

Alternative Names: AA-4500; AK-160; CCH; Clostridial collagenase; Collagenase clostridium histolyticum; Cordase; EN-3835; PF-5076985; Plaquase; XIAFLEX; Xiapex

Latest Information Update: 27 Mar 2017

Price : $50

At a glance

  • Originator BioSpecifics Technologies Corporation
  • Developer Actelion Pharmaceuticals; Asahi Kasei; BioSpecifics Technologies Corporation; Endo International; Swedish Orphan Biovitrum
  • Class Collagenases; Urologics
  • Mechanism of Action Collagen inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Dupuytren's contracture; Peyronie's disease
  • New Molecular Entity No
  • Available For Licensing Yes - Dupuytren's contracture; Peyronie's disease

Highest Development Phases

  • Marketed Dupuytren's contracture; Peyronie's disease
  • Phase II Cellulite; Frozen shoulder; Lipoma
  • Phase I Uterine leiomyoma
  • Preclinical Breast disorders
  • Research Metabolic disorders; Musculoskeletal disorders
  • Discontinued Hypertrophic scars; Keloids; Tendon injuries

Most Recent Events

  • 29 Mar 2017 BioSpecifics Technologies Corporation plans a clinical trial for Uterine leiomyoma in the first quarter of 2017
  • 15 Mar 2017 BioSpecifics Technologies plans a phase II trial for Cellulite in second half of 2017
  • 17 Nov 2016 Efficacy and adverse event data from a phase IIb trial in Cellulite released by BioSpecifics Technologies
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