NS 2359

Drug Profile

NS 2359

Alternative Names: 372475; GSK 372475

Latest Information Update: 14 Sep 2017

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At a glance

  • Originator NeuroSearch
  • Developer National Institute on Drug Abuse; Saniona; University of Pennsylvania
  • Class Antidepressants; Drug withdrawal therapies; Nootropics; Small molecules
  • Mechanism of Action Adrenergic uptake inhibitors; Dopamine uptake inhibitors; Serotonin uptake inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase II Cocaine abuse
  • Discontinued Alcoholism; Attention-deficit hyperactivity disorder; Major depressive disorder

Most Recent Events

  • 14 Sep 2017 Chemical structure information added
  • 19 Jul 2017 Phase-II development is ongoing for Cocaine abuse in USA (PO) (NCT02798627)
  • 01 May 2016 University of Pennsylvania initiates enrolment in a phase II trial for Cocaine abuse in USA (PO) (NCT02798627)
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