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Pexelizumab

Drug Profile

Pexelizumab

Alternative Names: 5G1.1-SC; Anti-C5 monoclonal antibody 5G1-1-SC; h5G1.1-scFV; Monoclonal antibody 5G1.1-SC; Short-acting monoclonal antibody 5G1.1

Latest Information Update: 29 Jul 2021

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At a glance

  • Originator Stanford University
  • Class Anti-inflammatories; Monoclonal antibodies
  • Mechanism of Action Complement C5 inhibitors; Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Discontinued Myocardial infarction; Reperfusion injury

Most Recent Events

  • 21 Jul 2021 Alexion Pharmaceuticals has been acquired by AstraZeneca and changed its name to Alexion AstraZeneca Rare Disease
  • 07 May 2007 Proctor & Gamble terminates its licence for pexelizumab worldwide
  • 28 Jun 2006 Interim results from a phase III clinical trial (APEX-AMI) in patients with myocardial infarction have been added to the Ischaemic Heart Disease therapeutic trials section
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