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ASN 002 - Ascend

Drug Profile

ASN 002 - Ascend

Alternative Names: Ad-IFNγ; Adenovirus interferon gamma; ASN-002 - Ascend; TG-1042

Latest Information Update: 26 Sep 2022

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At a glance

  • Originator Transgene
  • Developer Ascend Biopharmaceuticals; Nantes University Hospital; Transgene
  • Class Antineoplastics; Cancer vaccines; Immunotherapies; Synthetic vaccines
  • Mechanism of Action Immunostimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Cutaneous T-cell lymphoma; Basal cell nevus syndrome
  • New Molecular Entity No

Highest Development Phases

  • Phase II Basal cell cancer
  • No development reported Malignant melanoma
  • Discontinued Cutaneous B-cell lymphoma; Cutaneous T-cell lymphoma

Most Recent Events

  • 26 Sep 2022 Phase-II development is still ongoing for Basal cell cancer (Combination therapy, First-line therapy) in Australia (Intratumoural) (NCT04416516)
  • 23 Jul 2020 Phase-II clinical trials in Basal cell cancer (Combination therapy, First-line therapy) in Australia (Intratumoural) (NCT04416516)
  • 25 Sep 2019 Ascend Biopharmaceuticals plans a phase IIa trial for Basal cell cancer in Australia in October 2019 (ACTRN12619001298101)
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