Mepolizumab

Drug Profile

Mepolizumab

Alternative Names: 240563; Bosatria; Nucala; SB-240563

Latest Information Update: 12 Jan 2017

Price : $50

At a glance

  • Originator GlaxoSmithKline
  • Developer GlaxoSmithKline; McMaster University
  • Class Antiasthmatics; Monoclonal antibodies
  • Mechanism of Action Interleukin 5 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Hypereosinophilic syndrome; Churg-Strauss syndrome
  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

    No
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Asthma
  • Phase III Chronic obstructive pulmonary disease; Churg-Strauss syndrome; Hypereosinophilic syndrome
  • Phase II Nasal polyps
  • No development reported Eosinophilic oesophagitis

Most Recent Events

  • 05 Jan 2017 GlaxoSmithKline initiates a phase III pharmacokinetics trial for Asthma (In volunteers) in Germany (SC) (EudraCT2016-002405-19)
  • 23 Nov 2016 Adverse events and efficacy data from a phase III trial in Churg-Strauss syndrome released by GlaxoSmithKline
  • 01 Sep 2016 GlaxoSmithKline completes a phase III trial in in Churg-Strauss syndrome in USA, Belgium, Canada, France, Germany, Italy, Japan, Spain, and United Kingdom (NCT02020889)
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