RuplizumabAlternative Names: 5c8; 5c8 humanised monoclonal antibody; Anti-CD154 monoclonal antibody; Anti-CD40 ligand antibody; Anti-CD40 ligand monoclonal antibody; Anti-CD40 ligand monoclonal antibody 5c8; Anti-gp39 monoclonal antibody - Biogen; Antova; BG 9588; CD40 ligand monoclonal antibody - Biogen; hu5c8; Humanised CD40 ligand antibody/5c8; T cell-B cell activation molecule; T-BAM
Latest Information Update: 07 Mar 2007
At a glance
- Originator Biogen
- Class Monoclonal antibodies
- Mechanism of Action CD40 ligand inhibitors
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
On Fast track
Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.
- New Molecular Entity Yes
Highest Development Phases
- Discontinued Autoimmune disorders; Haemophilia A; Immune thrombocytopenic purpura; Multiple sclerosis; Renal transplant rejection; Systemic lupus erythematosus