Tocilizumab

Drug Profile

Tocilizumab

Alternative Names: Actemra; Anti-IL-6 receptor antibody - Chugai; Anti-interleukin-6 receptor antibody - Chugai; Atlizumab; HPM-1; MRA; MRA - Chugai; MRA-SC; R-1569; RG-1569; rhPM-1; RO4877533; RoActemra

Latest Information Update: 05 Jun 2017

Price : $50

At a glance

  • Originator Chugai Pharmaceutical; Osaka University
  • Developer Assistance Publique Hopitaux de Paris; Chugai Pharmaceutical; Hospital for Special Surgery; JW Pharmaceutical; Roche; University Hospital Inselspital; University of Bern; University of Pittsburgh
  • Class Antirheumatics; Monoclonal antibodies
  • Mechanism of Action Immunosuppressants; Interleukin 6 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Giant lymph node hyperplasia; Systemic scleroderma
  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Giant lymph node hyperplasia; Juvenile rheumatoid arthritis; Rheumatoid arthritis
  • Registered Giant cell arteritis
  • Preregistration Vasculitis
  • Phase III Osteoarthritis; Systemic scleroderma
  • Phase II Amyotrophic lateral sclerosis; Dermatomyositis; Polymyalgia rheumatica; Polymyositis
  • Phase I Chronic lymphocytic leukaemia
  • Discontinued Ankylosing spondylitis; Crohn's disease; Multiple myeloma; Pancreatic cancer; Systemic lupus erythematosus

Most Recent Events

  • 22 May 2017 Registered for Giant cell arteritis (Combination therapy) in USA (SC)
  • 18 May 2017 Phase-III clinical trials in Rheumatoid arthritis (Treatment-experienced, Combination therapy) in China (SC) before May 2017 (NCT03155347)
  • 18 May 2017 Phase-III clinical trials in Rheumatoid arthritis (Treatment-experienced, Monotherapy) in China (SC) before May 2017 (NCT03155347)
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