Research programme: clotrimazole analogues - Cyclacel/Lorus

Drug Profile

Research programme: clotrimazole analogues - Cyclacel/Lorus

Alternative Names: CYC-381; NC-169; NC-219; NC-381; NC-393; NC-394; NC-407; NuChem compounds

Latest Information Update: 17 Feb 2010

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At a glance

  • Originator Harvard University
  • Developer Cyclacel Pharmaceuticals
  • Class Imidazoles
  • Mechanism of Action Angiogenesis inhibitors; Mitosis inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Cancer

Most Recent Events

  • 25 Sep 2007 Preclinical development is ongoing
  • 28 Mar 2006 Xcyte Therapies has merged with Cyclacel to form Cyclacel Pharmaceuticals
  • 20 May 2005 This programme is still in active development
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