Drug Profile


Alternative Names: Acofide; Acotiamide hydrochloride hydrate; YM 443; Z-338

Latest Information Update: 27 Dec 2016

Price : $50

At a glance

  • Originator Zeria
  • Developer Astellas Pharma; Zeria
  • Class Benzamides; Gastrokinetics; Small molecules; Thiazoles
  • Mechanism of Action Acetylcholine stimulants; Acetylcholinesterase inhibitors; Muscarinic M1 receptor antagonists; Muscarinic M2 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • On Fast track

    Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Non-ulcer dyspepsia

Highest Development Phases

  • Marketed Non-ulcer dyspepsia

Most Recent Events

  • 01 Sep 2016 Astellas Pharma and Zeria Pharmaceutical initiates enrolment in a phase II trial for Non-ulcer dyspepsia in Japan (UMIN000023886)
  • 29 Jul 2015 No recent reports on development identified - Phase-II for Non-ulcer dyspepsia in Australia (PO)
  • 01 Mar 2014 Phase-III clinical trials in Non-ulcer dyspepsia in Belgium (PO)
Restricted Access

Oops, it looks like you don’t have a valid subscription to this content. To gain full access to the content and functionality of the AdisInsight database try one of the following.

  • with a username/password associated to an account with a valid subscription
  • Contact your organization’s admin about adding this content to your AdisInsight subscription
  • Request a trial

If you are a subscriber to this content then contact us at so we can help.

Back to top