Drug Profile


Alternative Names: CI 1034; PD 180988; PD 180988-0016

Latest Information Update: 12 Aug 2009

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At a glance

  • Originator Pfizer
  • Class Benzodioxoles; Heterocyclic compounds; Small molecules
  • Mechanism of Action Endothelin A receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Chronic obstructive pulmonary disease; Pulmonary hypertension

Most Recent Events

  • 31 Jul 2002 Phase-I/II clinical trials in Chronic obstructive pulmonary disease in USA (PO)
  • 02 Aug 2000 A preclinical study has been added to the Vascular Disorders pharmacodynamics section
  • 21 Jun 2000 Warner-Lambert has merged with Pfizer
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