Drug Profile


Alternative Names: APC-8015; APC8015F; Autologous PAP-loaded dendritic cell vaccine - Dendreon; Prostate cancer vaccine (APC-8015) - Dendreon; Provenge

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Dendreon Corporation
  • Class Cancer vaccines; Dendritic cell vaccines; T lymphocyte cell therapies; Tissue extracts
  • Mechanism of Action CD8 positive T lymphocyte stimulants; Immunostimulants; T lymphocyte stimulants
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity No

Highest Development Phases

  • Marketed Prostate cancer

Most Recent Events

  • 03 Jun 2017 Pharmacodynamics data from the phase II STAND, STRIDE and STAMP trials in Prostate cancer presented at the annual meeting of American Society of Clinical Oncology (ASCO-2017)
  • 01 Jun 2017 Dendreon terminates a phase II trial in Prostate cancer (Metastatic disease) in USA (NCT01338012) prior to June 2017
  • 13 May 2017 Sub-group efficacy analysis data from a phase IV trial in Prostate cancer released by Dendreon
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