Drug Profile


Alternative Names: DE-089; Diquafosol sodium; Diquafosol tetrasodium; Diquas; Diquas ophthalmic solution 3%; INS 365; INS 365 Ophthalmic; INS 365 Respiratory; KPY 998; Prolacria

Latest Information Update: 17 Nov 2017

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At a glance

  • Originator Inspire Pharmaceuticals
  • Developer Inspire Pharmaceuticals; Santen Pharmaceutical
  • Class Expectorants; Eye disorder therapies; Polyphosphates; Small molecules; Uracil nucleotides
  • Mechanism of Action Purinoceptor P2U agonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Dry eyes
  • Discontinued Bronchitis; Chronic obstructive pulmonary disease; Corneal ulcer; Cystic fibrosis

Most Recent Events

  • 01 Nov 2017 Registered for Dry eyes in China (Topical)
  • 09 Oct 2017 Santen Pharmaceutical plans a clinical trial for Dry eyes in Japan (UMIN000029333)
  • 08 Sep 2017 Phase-I clinical trials in Dry eyes in Taiwan (Opthalmic) (NCT03216096)
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