Tipiracil/trifluridine

Drug Profile

Tipiracil/trifluridine

Alternative Names: Lonsurf; S 95005/TAS-102; T15, T20; T15/T20; TAS-102; Trifluridine/tipiracil; Trifluridine/tipiracil hydrochloride

Latest Information Update: 17 Aug 2017

$50 / €47 *
* $ price applies to USA, Canada and Latin America. € price applies to the rest of the world. Final gross prices may vary according to local VAT.

At a glance

  • Originator Taiho Pharmaceutical
  • Developer 3SBio; Boehringer Ingelheim; Servier; Taiho Pharmaceutical
  • Class Antineoplastics; Nucleosides; Pyrimidines; Pyrrolidines; Small molecules
  • Mechanism of Action DNA synthesis inhibitors; Thymidine phosphorylase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    No
  • New Molecular Entity No

Highest Development Phases

  • Marketed Colorectal cancer
  • Phase III Gastric cancer
  • Phase II Oesophageal cancer; Small cell lung cancer
  • Phase I Gastrointestinal cancer; Solid tumours

Most Recent Events

  • 17 Aug 2017 Laboratorios Servier initiates enrolment in an early access phase IIIb trial for Colorectal cancer (Refractory metastatic disease) in Belgium (PO, Tablet) (EudraCT2016-002311-18) after September 2016
  • 16 Aug 2017 Servier and Amgen Australia plans a phase Ib/II PIT trial for Colorectal cancer (Combination therapy, Metastatic disease, Second-line therapy or greater) in Australia in September 2017 (ACTRN12617001190392)
  • 23 Jun 2017 Taiho Pharmaceutical plans the TRUSTY phase II/III trial for Colorectal cancer (Metastatic disease, Late-stage disease, Second-line therapy or greater) in Japan (JapicCTI-173618)
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