Drug Profile


Alternative Names: 2-Deoxyglucose; 2-DG

Latest Information Update: 20 Jul 2016

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At a glance

  • Originator Threshold Pharmaceuticals
  • Developer NeuroGenomeX; Threshold Pharmaceuticals; University of Wisconsin-Madison
  • Class Antineoplastics; Deoxy sugars
  • Mechanism of Action Antimetabolites; Glucose modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Preclinical Brain injuries; Epilepsy
  • Discontinued Solid tumours

Most Recent Events

  • 20 Jul 2016 Preclinical development is ongoing in Epilepsy and Brain injuries
  • 22 Apr 2009 Pharmacodynamics data from a preclinical study in Cancer presented at the 100th Annual Meeting of the American Association for Cancer Research (AACR-2009)
  • 01 May 2006 Data presented at the 97th Annual Meeting of the American Association for Cancer Research (AACR-2006) have been added to the pharmacokinetics and Cancer therapeutic trials sections
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