Drug Profile


Alternative Names: CLS-001; CPI-226; MBI-226; MBI-594AN; MX-226; MX-594AN; Omiganan pentachloride - BioWest; Omiganan pentahydrochloride; Omiganan pentahydrochloride 1% gel; Omigard

Latest Information Update: 04 Oct 2017

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At a glance

  • Originator MIGENIX
  • Developer Cadence Pharmaceuticals; Carrus Capital Corporation; Cutanea Life Sciences
  • Class Antibacterials; Antimicrobial cationic peptides
  • Mechanism of Action Cell membrane permeability enhancers
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes
  • Available For Licensing Yes - Catheter infections

Highest Development Phases

  • Phase III Rosacea
  • Phase II Acne vulgaris; Atopic dermatitis; Condylomata acuminata; Vulvar intraepithelial neoplasia
  • Phase I Dermatitis
  • Discontinued Catheter infections

Most Recent Events

  • 04 Jul 2017 Cutanea Life Sciences completes a phase II trial for Vulvar intraepithelial neoplasia in Netherlands (Topical) (NCT02596074)
  • 07 Mar 2017 Cutanea Life Sciences completes a phase-I trial in Healthy volunteers (Combination therapy, Monotherapy) in the Netherlands (NCT03071679)
  • 06 Feb 2017 Phase-I clinical trials in Dermatitis (In volunteers, Combination therapy, Monotherapy) in Netherlands (Topical) (NCT03071679)
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