Drug Profile


Alternative Names: BAY 10-8888; PLD 118

Latest Information Update: 15 Aug 2007

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At a glance

  • Originator Bayer; Bayer Yakuhin
  • Developer Bayer Yakuhin; PLIVA d.d.
  • Class Amino acids; Antifungals; Small molecules
  • Mechanism of Action Isoleucyl tRNA synthetase inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Discontinued Candidiasis; Vulvovaginal candidiasis

Most Recent Events

  • 20 May 2005 Phase-II clinical trials in Vulvovaginal candidiasis in USA (PO)
  • 31 Dec 2004 Phase-I clinical trials in Candidiasis in Germany (IV)
  • 31 Dec 2003 The first phase II trial has been successfully completed
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