PRO 140

Drug Profile

PRO 140

Alternative Names: Humanized monoclonal antibody to CCR5; PA-14; PRO-140

Latest Information Update: 16 Feb 2017

Price : $50

At a glance

  • Originator Progenics Pharmaceuticals
  • Developer CytoDyn; Progenics Pharmaceuticals; The Scripps Research Institute
  • Class Antivirals; Monoclonal antibodies
  • Mechanism of Action CCR5 receptor antagonists
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Phase III HIV infections
  • Phase II/III HIV-1 infections
  • Phase II Graft-versus-host disease

Most Recent Events

  • 01 Feb 2017 CytoDyn withdraws a phase II trial prior to enrollment due to lack of enrollment in HIV-1-infections (Adjunctive treatment) in USA (SC, Injection) (NCT01272258)
  • 01 Nov 2016 Phase-II clinical trials in Graft-versus-host disease in USA (IV) (NCT02737306)
  • 01 Oct 2016 CytoDyn initiates enrolment in a phase II/III extension trial for HIV infections in USA (NCT02990858)
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