Drug Profile


Alternative Names: JA 002; JA 002 - topical; WAP-8294A2

Latest Information Update: 30 Jun 2011

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At a glance

  • Originator aRigen
  • Class Antibacterials; Depsipeptides; Peptide antibiotics
  • Mechanism of Action Cell membrane modulators
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Phase I Methicillin-resistant Staphylococcus aureus infections
  • Preclinical Bacterial infections; Skin and soft tissue infections

Most Recent Events

  • 25 May 2009 Clinical development is ongoing in USA
  • 22 May 2009 WAP 8294A2 is no longer licensed to Janus Pharmaceuticals (now Topica Pharmaceuticals) in USA
  • 15 Apr 2005 Preclinical trials in Skin and soft tissue infections in USA (Topical)
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