Drug Profile


Alternative Names: BSF 223651; ILX 651; LU 223651; SYN-D; Synthadotin; Tasidotin HCl; Tasidotin hydrochloride

Latest Information Update: 05 Aug 2011

Price : $50

At a glance

  • Originator Abbott Bioresearch Corporation
  • Developer Genzyme Oncology; Sanofi Oncology
  • Class Antineoplastics; Oligopeptides; Small molecules
  • Mechanism of Action DNA topoisomerase inhibitors; Tubulin polymerisation inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.


Highest Development Phases

  • Phase I Malignant melanoma
  • Preclinical Solid tumours
  • Discontinued Non-small cell lung cancer; Prostate cancer

Most Recent Events

  • 28 Apr 2011 Phase-I clinical trials in Malignant melanoma in USA (PO)
  • 16 Mar 2010 Preclinical development is ongoing in USA
  • 06 May 2009 Genzyme Corporation and Ergomed agree to co-develop orally administered Tasidotin for Solid tumours
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