CLR 1404 I-131

Drug Profile

CLR 1404 I-131

Alternative Names: (131)I-CLR1404; 18-(p-[I-131]-iodophenyl)octadecyl phosphocholine; 131I-CLR1404; 131I-NM 404; CLR 131; CLR1404 I-131; HOT; I-131-CLR1404; NM404

Latest Information Update: 27 Jan 2017

Price : $50

At a glance

  • Originator University of Michigan Medical School
  • Developer Cellectar Biosciences; University of Wisconsin-Madison
  • Class Antineoplastics; Phospholipids; Radiopharmaceuticals; Small molecules
  • Mechanism of Action Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Multiple myeloma
  • New Molecular Entity No

Highest Development Phases

  • Phase I/II Non-small cell lung cancer
  • Phase I Multiple myeloma; Solid tumours

Most Recent Events

  • 14 Dec 2016 Cellectar Biosciences receives patent allowance for CLR 1404 I-131 in USA
  • 06 Dec 2016 Efficacy, adverse events and pharmacokinetics data from a phase I trial in Multiple myeloma presented at the 58th Annual Meeting of the American Society of Haematology (ASH-Hem-2016)
  • 03 Dec 2016 Efficacy, adverse events and pharmacodynamics data from a phase I trial in Multiple Myeloma presented at the 58th Annual Meeting and Exposition of the American Society of Hematology (ASH-2016)
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