CLR 1404 I-131

Drug Profile

CLR 1404 I-131

Alternative Names: (131)I-CLR1404; 18-(p-[I-131]-iodophenyl)octadecyl phosphocholine; 131I-CLR1404; 131I-NM 404; CLR 131; CLR1404 I-131; HOT; I-131-CLR1404; NM404

Latest Information Update: 18 Dec 2017

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At a glance

  • Originator University of Michigan Medical School
  • Developer Cellectar Biosciences; University of Wisconsin-Madison
  • Class Antineoplastics; Drug conjugates; Phospholipids; Radiopharmaceuticals; Small molecules
  • Mechanism of Action Ionising radiation emitters
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

    Yes - Multiple myeloma
  • New Molecular Entity No

Highest Development Phases

  • Phase II Haematological malignancies; Multiple myeloma
  • Phase I/II Non-small cell lung cancer
  • No development reported Solid tumours

Most Recent Events

  • 14 Dec 2017 Cellectar Biosciences files an IND application with the US FDA for Cancer (In children, In adolescents)
  • 14 Dec 2017 Cellectar Biosciences plans a phase I trial for Cancer (In children, In adolescents) in USA
  • 07 Nov 2017 Updated efficacy data from a phase I trial in Multiple myeloma released by Cellectar Biosciences
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