Drug Profile


Alternative Names: Arcoxia; Exxiv; L 791456 - Merck; MK 0663; MK 663

Latest Information Update: 10 Sep 2017

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At a glance

  • Originator Merck & Co
  • Developer Merck & Co; University of Regensburg
  • Class Antirheumatics; Non-opioid analgesics; Pyridines; Small molecules; Sulfones
  • Mechanism of Action Cyclo-oxygenase 2 inhibitors
  • Orphan Drug Status

    Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.

  • New Molecular Entity Yes

Highest Development Phases

  • Marketed Acute pain; Ankylosing spondylitis; Back pain; Dental pain; Dysmenorrhoea; Gouty arthritis; Musculoskeletal pain; Osteoarthritis; Postoperative pain; Rheumatic disorders; Rheumatoid arthritis
  • Phase III Surgical blood loss

Most Recent Events

  • 15 Mar 2016 Biomarkers information updated
  • 21 Jul 2015 Discontinued - Phase-III for Ankylosing spondylitis in Canada (PO)
  • 20 Jul 2015 Discontinued - Phase-III for Acute pain in USA (PO)
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